蘭州大學(xué)

翟紅林教授(ProfessorH.L.Zhai)，博士生導(dǎo)師，男，1964年4月出生。1986年6月蘭州大學(xué)化學(xué)系物理化學(xué)本科專業(yè)畢業(yè)獲學(xué)士學(xué)位并留校工作至今。2004年12月獲分析化學(xué)博士學(xué)位，2007年1月至2008年1月赴臺(tái)灣長(zhǎng)庚大學(xué)分子醫(yī)學(xué)研究中心開展抗癌藥物設(shè)計(jì)及癌癥診斷的博士后研究工作。目前主要從事復(fù)雜體系中的多組分同時(shí)定性與定量分析、實(shí)驗(yàn)條件優(yōu)化、藥物分子與蛋白質(zhì)相互作用模擬、藥物分子設(shè)計(jì)及計(jì)算機(jī)技術(shù)應(yīng)用等相關(guān)的教學(xué)與科研工作。在Analyst、AnalyticaChimicaActa、FoodChemistry、J.ChromatographyA、ChemometricsandIntelligentLaboratorySystems、J.ChemicalInformationandModeling、ChemicalBiology&DrugDesign、ComputationalBiology&Chemistry、ExpertSystemsWithApplications、J.Fluorescence等國(guó)內(nèi)外刊物上發(fā)表論文四十余篇；主研完成各類項(xiàng)目六項(xiàng)；目前主持國(guó)家自然科學(xué)基金面上項(xiàng)目一項(xiàng)。

近期發(fā)表的代表性論文：

1.B.Q.Li,J.Chen,J.J.Li,X.Wang,H.L.Zhai*.TheapplicationofTchebichefmomentmethodonthequantitativeanalysisofmultiplecompoundsbasedonthree-dimensionalHPLCfingerprintspectra.Analyst,2015,140(2):630-636.

2.J.Chen,B.Q.Li,H.L.Zhai*,W.J.Lü,X.Y.Zhang.ApracticalapplicationofwaveletmomentmethodonthequantitativeanalysisofShuanghuanglianoralliquidbasedonthree-dimensionalfingerprintspectra.JournalofChromatographyA,2014,1352:55-61.

3.H.L.Zhai*,B.Q.Li,Y.L.Tian,P.Z.Li,X.Y.Zhang.Anapplicationofwaveletmomentstothesimilarityanalysisofthree-dimensionalfingerprintspectraobtainedbyhigh-performanceliquidchromatographycoupledwithdiodedetector.FoodChemistry,2014,145:625-631.

4.H.L.Zhai*,Y.Y.Zhai,P.Z.Li,Y.L.Tian.Asimpleapproachtothequantitativeanalysisusingthree-dimensionalspectrabasedontheselectedZernikemoments.Analyst,2013,138(2):683-687.

5.H.L.Zhai*,Z.J.Shan,R.N.Li,EYu.Simultaneousquantitativeanalysisofthreecompoundsusingthree-dimensionalfluorescencespectrabasedondigitalimagetechniques.JournalofFluorescence,2012,22(4):1013-1019.

6.X.Y.Huang,Z.J.Shan,H.L.Zhai*,L.N.Li,X.Y.Zhang.Moleculardesignofanticancerdrugleadsbasedonthree-dimensionalquantitativestructure-activityrelationship.JournalofChemicalInformationandModeling,2011,51(8):1999-2006.

7.X.Y.Huang,Z.J.Shan,H.L.Zhai*,L.Shu,X.Y.Zhang.Studyontheanticanceractivityofcoumarinderivativesbymolecularmodeling.ChemicalBiology&DrugDesign,2011,78(4):651-658.

8.H.L.Zhai*,X.H.Wang,X.Y.Huang,Z.J.Shan.Theanalysisofcorepromotersequencesbasedontheirchemicalfeatures.ChemometricsandIntelligentLaboratorySystems,2011,107(2):245-250.

9.H.L.Zhai*,F.D.Hu,X.Y.Huang,J.H.Chen.Theapplicationofdigitalimagerecognitiontotheanalysisoftwo-dimensionalfingerprints.AnalyticaChimicaActa,2010,657:131-135.

10.H.L.Zhai*,Y.T.Chang,C.C.Wu,J.S.Yu*.Anapproachtotheeliminationofinter-individualvariabilityintumordetection.Analyst,2010,135:875-879.